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Longitudinal Metabolomics Profiling of Parkinsons Disease-Related Alpha-Synuclein A53T Transgenic Mice

To evaluate spermatogenesis and male fertility in mice, Computer-Aided Sperm Motion Analysis (CASA) was conducted on epididymal sperm to determine motility parameters, including the percentage of motile and forward progressive sperm

doi:10.1002/jimd.12593

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While the study concluded that short-term DSIP treatment was unlikely to be of major therapeutic benefit noting that statistically significant effects were weak and partly attributable to incidental placebo group change it provided the most methodologically rigorous human sleep architecture dataset for DSIP and confirmed the compounds specific effect on objective, not merely subjective, sleep quality parameters